主機部分包括中央處理器（CPU）、系統程序存儲器和用戶程序及數據存儲器。CPU是PLC的核心，它用以運行用戶程序、監控輸入/輸出接口狀態、作出邏輯判斷和進行數據處理，即讀取輸入變量、完成用戶指令規定的各種操作，將結果送到輸出端，并響應外部設備（如電腦、打印機等）的請求以及進行各種內部判斷等。PLC的內部存儲器有兩類，一類是系統程序存儲器，主要存放系統管理和監控程序及對用戶程序作編譯處理的程序，系統程序已由廠家固定，用戶不能更改；另一類是用戶程序及數據存儲器，主要存放用戶編制的應用程序及各種暫存數據和中間結果。
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